What is PAM50 (Prosigna)?

PAM50 (Prosigna) is a gene expression test that is used to analyze the activity of 50 genes in breast cancer cells. The test provides information about the risk of recurrence of early-stage breast cancer in postmenopausal women who have been diagnosed with hormone receptor-positive, HER2-negative breast cancer. It is used in combination with other clinical information, such as the size of the tumor and lymph node involvement, to help guide treatment decisions for early-stage breast cancer.